Piriformis Muscle Injection

Piriformis Muscle Injection

Persistent buttock pain that radiates down the leg is not always caused by a spinal condition. In many cases, the source of pain is the piriformis muscle — a small muscle located deep in the gluteal region that can irritate or compress the sciatic nerve.

At Nona Spine and Pain Institute, we offer piriformis muscle injections to reduce inflammation, relieve nerve compression, and restore mobility. Our physicians perform this procedure using ultrasound guidance, ensuring accurate needle placement within the muscle for both diagnostic precision and therapeutic effectiveness.

If sitting, walking, or climbing stairs triggers sharp buttock pain or radiating leg pain, piriformis syndrome may be the underlying cause.

Common Symptoms of Piriformis Syndrome

Patients with piriformis syndrome may experience:

  • Deep buttock pain
  • Pain that radiates down the back of the leg
  • Increased discomfort when sitting for long periods
  • Tenderness in the gluteal region
  • Limited hip mobility or stiffness

Because piriformis syndrome can mimic lumbar radiculopathy or herniated disc pain, an accurate diagnosis by a pain specialist is essential.


How a Piriformis Muscle Injection Works

A piriformis injection delivers anti-inflammatory medication directly into the piriformis muscle to reduce irritation and relieve pressure on the sciatic nerve.


Benefits of the Injection

The procedure helps to:

  • Reduce muscle inflammation
  • Relax muscle spasms
  • Relieve sciatic nerve irritation
  • Improve flexibility and hip movement

At Nona Spine and Pain Institute, the injection is performed using ultrasound imaging guidance to ensure precise medication delivery and optimal patient safety.

Many patients experience meaningful pain relief within a few days, with improved comfort during sitting, walking, and physical activity.


Who Is a Candidate for a Piriformis Injection?

You may benefit from a piriformis muscle injection if:

  • You experience persistent buttock pain with leg radiation
  • Pain worsens when sitting or climbing stairs
  • Stretching or physical therapy has not provided adequate relief
  • Oral medications provide limited improvement
  • Your symptoms suggest piriformis syndrome rather than spinal nerve compression

If your symptoms may also involve lumbar nerve irritation, your provider may recommend exploring spinal injection treatments as part of your comprehensive care plan.


Piriformis Syndrome Treatment in the Orlando Area


At Nona Spine and Pain Institute, we specialize in identifying the true source of sciatic-like pain. Our piriformis muscle injections are designed to provide targeted, minimally invasive relief so you can return to daily activities with greater comfort and mobility.

Our approach focuses on precision diagnosis, advanced imaging guidance, and evidence-based pain management treatments.


Schedule a consultation today to find out if a piriformis injection is right for you.